Sherlock Holmes

William Sherlock Scott "Sherlock" Holmes is one of the three protagonists, preceded by Madison Hunter and John Watson

Personality
Sherlock is most of the time heartless and not very attatched to anyone. However, he has become attached to John and Madison, seeing them more like family than friends. He has even cared for their children when they aren't available and they affectionately call him "Uncle Sherlock".

Siblings
He also has a strange relationship with his sister Eurus. He used to be close with her, but after spending so many times with Victor Trevor, Eurus became jealous of thier friendship, so she left him to die and he was the only friend Sherlock ever had.

Madison Hunter
With John, Sherlock sees Madison like family. Madison Hunter and John Watson

Watson siblings
Rosamund and Hunter Watson, affectionately called Rosie and Hunt, are cared by Sherlock when they aren't available and they affectionately call him "Uncle Sherlock". He calls them his niece and nephew in the epilogue.